KANGAR – Kematian seorang pelajar perempuan Sekolah Menengah Kebangsaan Syed Hassan di sini meninggalkan tanda tanya apabila pihak hospital dihalang daripada melakukan bedah siasat penuh selepas bapa mangsa berjaya mendapatkan perintah mahkamah.
Berdasarkan bedah siasat awal, doktor mendapati kematian A**** itu berpunca dari kegagalan hatinya berfungsi selepas tertelan pil panadol secara berlebihan.
Sebelum disahkan meninggal dunia, mangsa yang tidak sedarkan diri sejak Ahad lalu telah dimasukkan ke Unit Rawatan Rapi (ICU) Hospital Tuanku Fauziah (HTF) di sini.
Ketua Polis Daerah Kangar, Supritendan Abdul Rahman Mohd. Noordin berkata, bedah siasat awal mendapati, kematian mangsa disebabkan kegagalan hatinya berfungsi selepas tertelan pil tersebut.
PANADOL aka PARACETAMOL or acetamenophen
Generic Name: Paracetamol
Product Name: Panadol
YES, Paracetamol can cause poisoning if taken overdose can reach toxic level especially in children.
maka dengan itu, kalau nak ambil panadol aka paracetamol tu, kena la berhati dan tidak mengambilnya secara berlebih-lebihan kerana kesan sampingannya, terutamanya kepada hati (liver)
Jangan letak ubat atau pil itu merata-rata, takut budak-budak kecik boleh ambik & termakan...
ingat bahaya ok....
because it can cause PARACETAMOL POISONING
Paracetamol is a widely used over-the-counter analgesic (pain reliever) and antipyretic (fever reducer). However, its effectiveness alone as an antipyretic has been questioned. It is commonly used for the relief of headaches, and other minor aches and pains, and is a major ingredient in numerous cold and flu remedies. In combination with opioid analgesics, paracetamol could be used also in the management of more severe pain (such as in advanced cancer)
It could be considered a nonsteroidal antiinflammatory drugs (NSAID), but paracetamol has very little anti-inflammatory effect in many tissues. However aspirin, paracetamol and other NSAIDs all act by the same mechanism (inhibition of prostaglandin (PG) synthesis) and all show varying levels of analgesic, anti-inflammatory, antipyretic and antiplatelet actions.
The toxic dose of paracetamol is highly variable. In adults, single doses above 10 grams or 200 mg/kg of bodyweight, whichever is lower, have a reasonable likelihood of causing toxicity.Toxicity can also occur when multiple smaller doses within 24 hours exceeds these levels
The signs and symptoms of paracetamol toxicity occur in three phases. The first phase begins within hours of overdose, and consists of nausea, vomiting, pallor, and sweating.However, patients often have no specific symptoms or only mild symptoms in the first 24 hours of poisoning. Rarely, after massive overdoses, patients may develop symptoms of metabolic acidosis and coma early in the course of poisoning.
The second phase occurs between 24 and 72 hours following overdose and consists of signs of increasing liver damage. In general, damage occurs in hepatocytes as they metabolize the paracetamol. The individual may experience right-upper-quadrant pain. The increasing liver damage also alters biochemical markers of liver function; International normalized ratio (INR) and the hepatic transaminases alanine transaminase and aspartate transaminase rise to abnormal levels. Acute kidney failure may also occur during this phase, typically caused by either hepatorenal syndrome or multiple organ dysfunction syndrome. In some cases, acute kidney failure may be the primary clinical manifestation of toxicity. In these cases, it has been suggested that the toxic metabolite is produced more in the kidneys than in the liver.
The third phase follows at 3 to 5 days, and is marked by complications of massive hepatic necrosis leading to fulminant hepatic failure with complications of coagulation defects,hypoglycemia, kidney failure, hepatic encephalopathy, cerebral edema, sepsis, multiple organ failure, and death. If the third phase is survived, the hepatic necrosis runs its course, and liver and kidney function typically return to normal in a few weeks The severity of paracetamol toxicity varies depending on the dose and whether appropriate treatment is received.
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